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Study Finds Increase In Use Of Donor Eggs For In Vitro Fertilization

Update Date: Oct 18, 2013 05:29 AM EDT

The number of donor eggs used in vitro fertilization has increase in U.S between 2000 and 2010, a study finds. Also the outcomes from those donor eggs produced often good results.

In the study it was found that the increment took place from 19 percent in 2000 to 25% in 2010.

During the past few decades, the number of live births to women in their early 40s has increased gradually. In vitro fertilization the prevalence of oocyte (egg) donation has increased too in the U.S.

The trends in use of donor oocytes in United States were examined as a part of the research. The parental outcomes too were assessed.

Study led by Jennifer F. Kawwass, M.D., of the Emory University School of Medicine, Atlanta, used the data from Centers for Disease Control and Prevention’s National Assisted Reproductive Technology (ART) Surveillance System (NASS). As fertility centres are now required to report their data to the system, researchers had the access to 95% of all IVF cycles performed in the United States.

“Use of donor oocytes is an increasingly common treatment for infertile women with diminished ovarian reserve for whom the likelihood of good perinatal outcome appears to be independent of recipient age. To maximize the likelihood of a good perinatal outcome, the American Society of Reproductive Medicine recommendations suggesting transfer of a single embryo in women younger than 35 years should be considered,” authors wrote.

Standard measure of good perinatal outcome was defined as single live-born infant which is delivered at 37 weeks or weighed 5.5 lbs or more after birth.

Additional studies evaluating the mechanisms by which race/ethnicity, infertility diagnosis, and day of embryo culture affect perinatal outcomes in both autologous [donor and recipient are the same person] and donor IVF pregnancies are warranted to develop preventive measures to increase the likelihood of obtaining a good perinatal outcome among ART users," the authors added.

The study is published online in the journal of JAMA.

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