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Grapes Compound Helps Offset Adverse Effects of High Fructose Diet, Study Finds

Update Date: Feb 04, 2013 07:19 AM EST

A new study has found that supplementing high fructose diet with grape polyphenol (PP) can help against health complications caused by a diet high in fructose.

Fructose, commonly known as fruit sugar, is preferred over other types of sugars in the food industry because it is cheap and more sweet than the rest. Consumption of fructose in large amounts has been associated with obesity and metabolic syndrome. Previous research says that High Fructose Corn Syrup added in food leads to overconsumption of calories that results in increased weight.

A related study had shown that a diet rich in fructose can lead to an increase in high cholesterol and decreased insulin sensitivity in obese or overweight adults.

The small study included 38 adults who were overweight or obese and at high metabolic risk. All the participants had a close relative who was diagnosed with diabetes type-2.

Researchers found that participants who were on a fructose diet along with grapes polyphenols didn't have the long-term health complications of high fructose like decreased insulin sensitivity, compared to people who were on placebo along with high fructose.

Study results showed that people who were on placebo had a 20 percent reduction in hepatic insulin sensitivity index and an 11 percent low glucose infusion rates, both of which are associated with diabetes type-2.

"Future studies should investigate the effects of grape PP coadministration with processed food rich in fructose and their potential role in counteracting the metabolic syndrome," the authors wrote, reports HealthDay.

The study is published in the journal Diabetes Care

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