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Health Benefits of Broccoli and How It May Reduce Cancer Risks [VIDEO]

Update Date: Mar 20, 2017 07:16 AM EDT
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California Town Of El Centro Struggles With Highest US Unemployment Rate
EL CENTRO, CA - MARCH 12: Mexican-American farm workers harvest broccoli March 12, 2009 near El Centro, California. El Centro is suffering the highest unemployment rate in the nation at 22.6 percent, nearly as high as rates during the Great Depression, with Latinos especially being hit hard. The people of the Imperial Valley, an important food producing region in the desert north of the US-Mexico border and east of San Diego, are plagued with a devastating combination of drought, which has farmers desperate for water; a construction-idling housing bust; and a plummeting peso, which undercuts the buying power of Mexicans who shop on the U.S. side of the border. On top of that, California is reeling from a massive budget crisis that ushered in higher taxes and deep cuts to programs and services statewide. (Photo : Photo by David McNew/Getty Images)

Researchers found a compound present in broccoli, sulforaphane, which is found to be capable of preventing and treating cancer. The compound is also present in other cruciferous vegetables and proved to play a big role in preventing prostate cancer cells from spreading.

A research conducted at the Oregon State University revealed that the sulforaphane compound present in broccoli can reduce long noncoding RNA's present in prostate cancer cells. RNA's are metastatic and can also lead to developing several other types of cancers in the breast, stomach, and the lungs.

This discovery can open up a new range of dietary options, foods, drugs and strategies, derived from the compound, that can help preventing cancer cells from spreading, or eventually annihilating it, the Medical News Today reported.

IncRNAs are cells that can regulate gene expression in the body. If this occurs, genes are switched irregularly preventing them from doing their jobs properly. As the IncRNA's becomes dysregulated, spreading of cancer cells develop. The role of IncRNA's proves to be very significant, thus targeting this cells through the sulforaphane present in broccoli is a remarkable discovery.

Prostate cancer cells show a high expression of IncRNA's called LINC01116. In the experiment, administering sulforaphane to the prostate cancer cells reduced expression levels and lead to a fourfold reduction in the cells' capabilities to form colonies, MidDay cited.

Prostate cancer is considered as the second most frequently diagnosed form of cancer in men around the globe. Treating prostate cancer with sulforaphane could normalize the levels of IncRNA in the body. This experiment also reinforces a new avenue for chemoprevention research and chemicals that can be derived from natural sources that can alter cancer cells.

Results of the experiment suggest that an increased consumption of cruciferous vegetables such as broccoli lower the risk of developing prostate cancer. This may also offer a new way of specifically treating prostate cancer or preventing cancer from ever occurring.


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