Mental Health

Vitamin D Deficiency May Double Schizophrenia Risk

By Christine Hsu | Update Date: Jul 23, 2014 09:48 PM EDT

Not getting enough vitamin D can double the risk of schizophrenia, according to a new study.

Researchers analyzed 19 observational studies, which involved 2,804 adult participants, evaluating the link between vitamin D and schizophrenia and found that schizophrenics had significantly lower levels of vitamin D in the blood compared to the control groups.

Researchers found that the average difference in vitamin D levels between schizophrenic patients and those with adequate vitamin D in their bloodstreams was -5.91 ng/ml. They found that people with vitamin D deficiency were 2.16 times more likely to be schizophrenic than those with sufficient levels.

Furthermore, 65 percent of participants who had schizophrenia were also vitamin D deficient.

"This is the first comprehensive meta-analysis to study the relationship between the two conditions," researcher Ahmad Esmaillzadeh, PhD, of the Isfahan University of Medical Sciences in Isfahan, Iran, said in a news release. "When we examined the findings of several observational studies on vitamin D and schizophrenia, we found people with schizophrenia have lower vitamin D levels than healthy people. Vitamin D deficiency is quite common among people with schizophrenia."

"There is a growing trend in the nutrition science field to consider vitamin D and its relationship to conditions such as diabetes, cancer, heart disease and depression," Esmaillzadeh said. "Our findings support the theory that vitamin D may have a significant impact on psychiatric health. More research is needed to determine how the growing problem of vitamin D deficiency may be affecting our overall health."

The latest findings are published in the Journal of Clinical Endocrinology & Metabolism.

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