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Two sisters from Mount Horeb have filed a federal claim that says that a cervical cancer vaccine shut down their ovaries. They also claim that the vaccine has almost left them unable to get pregnant too.

The condition of the two Wisconsin sisters came from the Gardasil vaccine which is taken for the HPV (human papillomavirus).

HPV is a sexually transmitter virus whose vaccine is recommended for three doses. The two available brands were Cervarix, approved in 2009 and Gardasil, approved in 2006.

Their attorney, Mark Krueger, told the newspaper it is the first allegation of its kind to reach a hearing through the National Vaccine Injury Compensation Program, a special court established to evaluate claims of harm from vaccines, reports CBSNews.

After the allegations were made, the vaccine’s maker issued the statement. In the statement they made it clear that there wasn’t any possible relationship that existed between the condition and vaccine.

According to Centers for Disease Control and Prevention and the Food and Drug Administration, the vaccine is completely safe and helps in preventing around 18,000 cancers in women and 8,000 cancer in men every year.

Till now the vaccine injury program has awarded payments for HPV vaccine in total 68 cases. This account to total of at least $5.9 million, according to according to the federal government and Judicial Watch which is a nonpartisan foundation.

The program has dismissed 63 cases and 81 are still pending.

Madelyne Meylor, 20, and Olivia Meylor, 19, both believe that Gardasil shots caused their ovaries to stop producing eggs. They also have premature menopause, marked by insomnia, night sweats and headaches, and almost certainly won’t be able to get pregnant, they said according to CBSNews.

“I’ve always wanted a huge family, but I don’t know if that will be possible,” Madelyne Meylor said according to CBSNews.